Diabetes prevention: Reproductive age women affected by insulin resistance
نویسندگان
چکیده
منابع مشابه
Prevention of Type 2 Diabetes Insulin Resistance and -Cell Function
Type 2 diabetes is increasing worldwide in epidemic proportions. Its associated morbidity and mortality is imposing a major burden on the health care system. Based on a better understanding of the pathophysiology of glucose intolerance, clinical trials on the prevention of diabetes have been performed. It has now been demonstrated that diet and exercise, metformin, acarbose, and troglitazone ca...
متن کاملOn diabetes: insulin resistance
Insulin is the most potent anabolic hormone known and is essential for appropriate tissue development, growth, and maintenance of whole-body glucose homeostasis. This hormone is secreted by the β cells of the pancreatic islets of Langerhans in response to increased circulating levels of glucose and amino acids after a meal. Insulin regulates glucose homeostasis at many sites, reducing hepatic g...
متن کاملOn diabetes: insulin resistance
The association of obesity with type 2 diabetes has been recognized for decades, and the major basis for this link is the ability of obesity to engender insulin resistance. Insulin resistance is a fundamental aspect of the etiology of type 2 diabetes and is also linked to a wide array of other pathophysiologic sequelae including hypertension, hyperlipidemia, atherosclerosis (i.e., the metabolic...
متن کاملOn diabetes: insulin resistance
The pathogenesis of type 2 diabetes is characterized by two major features: peripheral insulin resistance and impaired insulin secretion from pancreatic β cells (1, 2). The application of transgenic mouse technology to the study of diabetes has been extensively reviewed (3). Here, I review the application of a complementary approach, gene knockout technology, to the problem of understanding ins...
متن کاملOn diabetes: insulin resistance
In this paper I review the evidence that human sensitivity to insulin is influenced by heredity, in particular by one or more genes with relatively large effects. Even granting the existence of such genes, however, the best route toward identifying them — and the related genes that are presumed to affect an individual’s risk of obesity or type 2 diabetes — remains unclear. Thus, the phenotype o...
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ژورنال
عنوان ژورنال: Women's Health
سال: 2016
ISSN: 1745-5065,1745-5065
DOI: 10.1177/1745505716653691